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Cake day: July 9th, 2023

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  • Everyone is talking about dominant and recessive genes, so I just want to clarify a couple things.

    The way your body directly uses genes is as a blueprint to construct proteins. Your cells are always producing proteins from the genes in all your chromosomes. It has complex ways of regulating how much of each it produces, but your body doesn’t care what chromosome it’s coming from. Once an embryo is fertilized, there’s really no distinction between “mom” chromosomes or “dad” chromosomes, as far as the embryo and its protein machinery are concerned.

    “Dominant” and “recessive” characterization is about how those proteins affect your body at the macro scale, not whether your body actually uses the gene and produces its proteins – it always does that. For example, brown hair is a dominant trait, and blonde is recessive. But this is because producing any amount of brown pigment will make your hair brown, regardless of what other pigments you’re making, simply because it’s darker. Literally the same as combining blonde and brown paint. It has nothing to do with whether the genes are actually being expressed – the brown hair gene doesn’t stop the blonde hair gene from making its pigments.














  • The size of the code is mostly irrelevant if you’re not shipping it to clients over the network on every request. Short of truly gargantuan statically-linked binaries in compiled languages, anyway, and bundling isn’t really an applicable concept there. And similarly, the overhead of loading modules from the filesystem is a one-time cost that’s mostly irrelevant for server-side code that runs for days or weeks or years at a time.

    On the other hand, the complexity overhead of adding the additional bundling step is a major drag on development productivity, debuggability, etc.