In a pioneering study, researchers from Harvard Medical School, University of Maine, and MIT have introduced a chemical method for reversing cellular aging. This revolutionary approach offers a potential alternative to gene therapy for age reversal. The findings could transform treatments for age-re

Age Reversal Breakthrough: Harvard/MIT Discovery Could Enable Whole-Body Rejuvenation::In a pioneering study, researchers from Harvard Medical School, University of Maine, and MIT have introduced a chemical method for reversing cellular aging. This revolutionary approach offers a potential alternative to gene therapy for age reversal. The findings could transform treatments for age-re

        • Stovetop@lemmy.worldEnglish
          4·
          1 year ago

          The other implication of that show is that you need to keep paying, even after you’re dead. You are no longer earning anything in the afterlife and are entirely dependent on having family/friends/loved ones continue paying for your access to the upper tier. But once the “second death” where people forget about you happens, the poor experience is inevitable, and you accept that you’re nothing more than a scanned consciousness to be used by this corporation for profit.

      • rasikww@lemmy.worldEnglish
        3·
        1 year ago

        I like how you only mentioned the first season, I didn’t watch season 2 at all…

      • LibertyLizard@slrpnk.netEnglish
        81·
        1 year ago

        All technology is initially available to only the rich. But it can be widely available, if people demand it.

        Also, those pills don’t work anyway so don’t get too worried yet.

      • TWeaK@lemm.eeEnglish
        413·
        1 year ago

        Peter Thiel and probably Donald Trump have supposedly been injecting themselves with children’s blood, or at least a derivative from their blood.

    • Piecemakers@lemmy.worldEnglish
      41·
      1 year ago

      Jokes aside, are we just cribbing from sci-fi cart blânche these days?! I mean, sure “Art imitates Life imitates Art”, but still. When the only dead are the poors (>99% of humanity itself), the entire species will certainly collapse. (Where’s the “bridge of nose pinch + sigh” emoji when you need it?) 🤷🏼‍♂️

      • LibertyLizard@slrpnk.netEnglish
        3·
        1 year ago

        All technology is initially available to only the rich. But it can be widely available, if people demand it.

        Also, those pills don’t work anyway so don’t get too worried yet.

          • LibertyLizard@slrpnk.netEnglish
            1·
            1 year ago

            I don’t really understand this viewpoint but treatments for aging won’t make you immortal which is almost certainly impossible. You’ll still die, you’ll just be healthier for a longer period, possibly a much longer period.

          • Tesco@lemmy.worldEnglish
            1·
            1 year ago

            At first it isn’t, but as you go more and more grey it becomes a lot harder to manage on your own, especially if you started with dark hair. It’s depressing to be young and constantly fighting a losing battle against the grey. I was like 16 when it started, by my very early 30s the whole of the top of my hair was completely grey.

  • drapermache@lemmy.worldEnglish
    79·
    1 year ago

    Couldn’t you wait until Mitch Mconnell died until you released this? I’d rather not him be in the senate forever.

  • evranch@lemmy.caEnglish
    65·
    1 year ago

    Full text of actual paper: https://www.aging-us.com/full/204896

    Tldr; seems like decent science and the compounds used are fairly ordinary ones for the most part. Note however this is all in vitro so far and it might be a challenge to deliver the same chemicals in the same concentrations to all the senescent cells of the body.

    Prepare to see these ingredients added in insignificant amounts to expensive skin creams before the year is out, whether they can penetrate the epidermis or not

    • belshamharoth@lemmy.worldEnglish
      8·
      1 year ago

      The full journal article says “in vivo” not “in vitro”. They have already successfully regenerated mice which are organisms biologically similar to humans.

      Edit

      I was wrong about this. The journal article does only talk about results obtained “in vitro” but mentions other studies that have successfully reversed cellular ageing “in vivo”.

      The ability of the Yamanaka factors to erase cellular identity raised a key question: is it possible to reverse cellular aging in vivo without causing uncontrolled cell growth and tumorigenesis? Initially, it didn’t seem so, as mice died within two days of expressing OSKM. But work by the Belmonte lab, our lab, and others have confirmed that it is possible to safely improve the function of tissues in vivo by pulsing OSKM expression [22, 23] or by continuously expressing only OSK, leaving out the oncogene c-MYC

      So in this study the results were only in vitro but other studies have successfully reversed cellular ageing in vivo.

    • foggy@lemmy.worldEnglish
      2·
      1 year ago

      Worry? I’m excited for it man.

      They don’t realize they’re messing with a monkeys paw.

      The first gen lifers are gonna live to regret their discovery.

  • CaffeinatedOne@lemmy.worldEnglish
    444·
    1 year ago

    Even if for the rich, this would be good news. The rich and powerful will stop ignoring things like distant climate related deadlines, if they think they’ll be alive to feel their effects.

    • BastingChemina@slrpnk.netEnglish
      7·
      1 year ago

      I honestly don’t think so. I don’t think they care of the condition worsen, including theirs as long as they stay above the poorer people.

      Like, if we look at the living condition of a medieval era king. You live in a stone castle do your bedroom as freezing temperature in winter, terrible healthcare so you might be in terrible pain for things that easily treatable, no hygiene the smells everywhere must be horrible… Compared with the comfort of a normal person in a developed country. ( Not the US though, now like Denmark or Switzerland) the modern life is clearly way more comfortable.

      However I suspect that a lot of people, especially richer people would prefer to be the king, despite the conditions.

    • insta11@lemmy.worldEnglish
      1·
      1 year ago

      If this take is anything like whales with stock they’ll just jump ship onto the next country/planet to start over it’s a never ending cycle

      A lot of the rich/ultra wealthy are selfish and don’t give a fuck unless it directly affects them so I don’t foresee any accountability if the planet Implodes instead they’ll just fling their money at the next thing that buys them a ticket out of here

  • zensoup@lemmy.worldEnglish
    332·
    1 year ago

    Ahh, immortal super-rich people whose views get more and more conservative as they age forever… What an exciting future to look forward to!

    • CodeInvasion@sh.itjust.worksEnglish
      271·
      1 year ago

      The only upside I can think of is they’d actually start caring about the planet instead of thinking they’ll be dead in 100 years anyway.

      • gdrhnvfhj@lemmynsfw.comEnglish
        2·
        1 year ago

        They try to get so rich no matter what, so they can evade all consequences. (That’s not possible, but they want to believe it)

    • TheCraiggers@lemmy.worldEnglish
      8·
      1 year ago

      I see one potential good thing though: maybe people would be less interested in killing the only planet that supports human life if they knew they were going to be on it forever.

  • RandomBit@lemmy.sdf.orgEnglish
    231·
    1 year ago

    The sci-fi type implications of this would be astounding. We would see a rapidly increasing global population with high natural resource use. On a philosophical level, is living forever a blessing or a curse?

        • ☆Luma☆@lemmy.caEnglish
          5·
          1 year ago

          Wouldn’t want them to miss out of their fun for a moment! Now they can torture generations of people~

        • AB7ORH7D@lemmy.worldEnglish
          1·
          1 year ago

          With term limits of course. Idk there could be a possibility that they’d take the planet seriously though as they’d be around to see the consequences of environmental policy

          • InverseParallax@lemmy.worldEnglish
            2·
            1 year ago

            Idk there could be a possibility that they’d take the planet seriously though as they’d be around to see the consequences of environmental policy

            I’m more of the school of thought that “THERE CAN BE ONLY ONE!!!” and in the grim dark future of immortal oligarchs, there is only war.

    • Kes@lemmy.blahaj.zoneEnglish
      2·
      1 year ago

      It’s not a path to living forever; cells can’t reproduce once they burn through their telemeres. What this is is a way to have a youthful body at an older age so you won’t spend the last years of your life frail and wrinkly

      • Meldroc@lemmy.worldEnglish
        3·
        1 year ago

        I’m betting any genuine anti-aging therapy is going to be a complex mess of many treatments. Top off the telomeres, error-correct the DNA, roto-rooter the arteries, reprogram cells, etc…

    • Stovetop@lemmy.worldEnglish
      1·
      1 year ago

      I doubt that will be the reality of any such breakthroughs, at least not for a long time. But I think the solution in such a scenario would have to be sterilization of everyone on earth by default. Sterilization which could be temporarily reversed to allow someone to have a child via a controlled application process just to meet the rate of replacement.

      • TWeaK@lemm.eeEnglish
        4·
        1 year ago

        Sometimes paywalls only hit you after you’ve visited a handful of articles.

  • Shaggy0291@lemmygrad.mlEnglish
    13·
    1 year ago

    Biochemist here, It’s almost certainly an overhyped study. The operative term being used here is “potentially” full body rejuvenation is possible. It doesn’t address issues such as administration of the therapy in tissues with virtually no turnover rate, including cardiac tissue, skeletal muscle, and nervous tissue. You cannot renew something that the body doesn’t naturally replace via the cell cycle.

    • cottard@lemmy.worldEnglish
      3·
      1 year ago

      Thanks for reminding me to prioritize the capacity for dignified exit from the game.

  • nitefox@lemmy.worldEnglish
    101·
    1 year ago

    The comments be like: I didn’t read the article, here my pissed off reaction calling for 1984

  • LibertyLizard@slrpnk.netEnglish
    91·
    1 year ago

    Before people lose their minds, this research, while interesting, is very far from true aging reversal. At most it could be one aspect of it.